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Research Interests
I'm passionate about understanding evolutionary forces such as natural selection and random genetic drift and how they drive patterns of genetic diversity and differentiation. I'm also particularly interested in technical aspects, i.e. in developing novel tools and methods required to tackle these and other evolutionary questions. The technical revolution of next-generation sequencing has opened up entirely new possibilities, which I was able to explore for my doctoral degree. Using a population genomics approach, I investigated the demographic history and local adaptations of orangutans - the most basal great apes to humans. More broadly, I’m interested in personalized medicine and forensic techniques, as well as in several other fields including biodiversity and conservation.
Zurich Open Repository and Archive
ZORA Publication List
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Publications
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Evidence that the rate of strong selective sweeps increases with population size in the great apes Proceedings of the National Academy of Sciences of the United States of America, 114(7):1613-1618.
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Evolution and demography of the great apes Current Opinion in Genetics & Development, 41:124-129.
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Tandem repeat variation in human and great ape populations and its impact on gene expression divergence Genome Research, 25(11):1591-1599.
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Reconstructing the demographic history of orang-utans using Approximate Bayesian Computation Molecular Ecology, 24(2):310-327.
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Marked population structure and recent migration in the critically endangered Sumatran orangutan (Pongo abelii) Journal of Heredity, 104(1):2-13.
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Polymorphic microsatellite loci for the endangered pine hoverfly Blera fallax (Diptera: Syrphidae) Conservation Genetics Resources, 4(1):117-120.
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Genetic variation and population decline of an endangered hoverfly Blera fallax (Diptera: Syrphidae) Conservation Genetics, 13(5):1283-1291.
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The quest for Y-chromosomal markers – methodological strategies for mammalian non-model organisms Molecular Ecology Resources, 10(3):409-420.
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A multiplex-system to target 16 male-specific and 15 autosomal genetic markers for orang-utans (genus: Pongo) Conservation Genetics Resources, 2(S1):153-158.
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Development of polymorphic microsatellite markers for the dung fly (Sepsis cynipsea) Molecular Ecology Resources, 9(6):1554-1556.